SUPERNOVA
Can extracorporeal carbon dioxide removal (ECCO2R) safely facilitate ultra-low tidal volume ventilation in patients with moderate acute respiratory distress syndrome (ARDS)?
Continue reading »Category: Emergency Medicine
A collection of TBL summaries relevant to Emergency Medicine
ANDROMEDA-SHOCK
In adult patients with early septic shock, does peripheral perfusion-targeted resuscitation, compared to lactate level-targeted resuscitation, improve all cause mortality at 28 days?
Continue reading »TICH-2
In adults with acute, spontaneous intra-cerebral haemorrhage (ICH), does the administration of tranexamic acid (TXA) compared to a placebo improve functional status at 90 days?
Continue reading »CENSER
In patients with septic shock, does early low-dose norepinephrine compared with standard care increase shock control at six hours?
Continue reading »Pivetta
In patients who presented to the Emergency Department (ED) with acute dyspnoea, does the addition of lung ultrasound examination compared to standard approach, improve the diagnostic accuracy for acute decompensated heart failure (ADHF)?
Continue reading »The IRIS Cricoid Trial
In patients undergoing rapid sequence anaesthesia induction, does the use of cricoid pressure vs. a sham procedure, prevent pulmonary aspiration?
Continue reading »RACE
Do one or more doses of levocarnitine reduce organ failure in septic shock at 48 hours, compared with placebo?
Continue reading »Don’t forget the LEGO
In adult subjects who ingest a small toy part, compared to historical controls of children who have ingested coins, is there a difference in object transit time and complication rate?
Continue reading »PReVENT
In mechanically ventilated patients without acute respiratory distress syndrome (ARDS), does a low tidal volume ventilation strategy (6mL/Kg), compared to intermediate tidal volume strategy (10mL/Kg), reduce the number of ventilator-free and alive days at day 28?
Continue reading »POLAR
In patients with severe blunt traumatic brain injury (TBI) does early and sustained cooling compared with standard care improve neurological outcomes at 6 months?
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