6S
In critically ill adults with severe sepsis, does 6% hydroxyethyl starch (HES) compared to Ringer’s acetate reduce the incidence of death or end stage kidney failure?
Continue reading »Tag: Fluid
SHoC-ED
In selected non-trauma patients presenting to the emergency department with undifferentiated hypotension, does a standardised point-of-care ultrasound protocol, compared with usual care, improve 30 day or hospital survival?
Continue reading »RELIEF
In adult patients undergoing major elective abdominal surgery, does a restrictive fluid regimen compared with a liberal fluid regimen reduce complications and improved disability-free survival?
Continue reading »SALT-ED
In non-critically ill adult patients admitted to hospital from the Emergency Department, does the administration of a balanced salt solution compared with normal saline, reduce hospital free days to day 28?
Continue reading »SMART
In critically ill patients does the administration of balanced crystalloids compared with saline, reduce a 30 day composite outcome of death, new renal replacement therapy or persistent renal dysfunction?
Continue reading »PRESERVE
In high-risk patients undergoing angiography, does the administration of bicarbonate and/or acetylcysteine, compared with placebo, prevent major adverse events and acute kidney injury?
Continue reading »SSSP2
In Zambian adults with sepsis and hypotension, does a resuscitation protocol implemented early after presentation to the Emergency Department improve in-hospital mortality compared with usual care?
Continue reading »Corl
In fluid responsive spontaneously breathing critically unwell patients undergoing resuscitation, does the collapsibility of the inferior vena cava (cIVC), as determined by point of care ultrasound (POCUS), when compared to administering a fluid bolus predict a >10% increase in cardiac output?
Continue reading »POCUS: Feissel
In patients with septic shock who are mechanically ventilated does indexed LV end-diastolic area and respiratory changes in aortic blood velocity predict the haemodynamic effects of volume expansion?
Continue reading »POCUS: Moretti
In mechanically ventilated patients with subarachnoid hemorrhage (SAH), does the distensibility of IVC on ultrasound, predict fluid responsiveness measured by thermodilution?
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