Tag: Neurology

TICH-2

In adults with acute, spontaneous intra-cerebral haemorrhage (ICH), does the administration of tranexamic acid (TXA) compared to a placebo improve functional status at 90 days?

POLAR

In patients with severe blunt traumatic brain injury (TBI) does early and sustained cooling compared with standard care improve neurological outcomes at 6 months?

EXTEND IA TNK

8 June 2018 Fraser Magee Emergency Medicine, Intensive Care Medicine Leave a comment

In patients with anterior circulation strokes undergoing endovascular thrombectomy, is IV thrombolysis within 4.5 hours of stroke onset with tenecteplase, non-inferior to alteplase, at establishing reperfusion?

DAWN

11 May 2018 Anthony Hackett Emergency Medicine, Summaries Leave a comment

In patients who are 6-24 hours post acute stroke, and have a mismatch between clinical deficit and infarct, does thrombectomy plus standard medical care, compared to standard medical care alone, improve functional outcomes at 90 days?

Gujjar

20 April 2018 David Slessor Emergency Medicine Leave a comment

In patients with status epilepticus (SE) and cluster attacks of seizures, (CS) does IV levetiracetam vs. IV phenytoin improve rate of control of seizures?

DEFUSE 3

30 March 2018 Anthony Hackett Emergency Medicine Leave a comment

In patients with proximal internal carotid (ICA) or middle cerebral artery (MCA) occlusion with likely salvageable ischaemic brain tissue, does thrombectomy, at 6-16 hours post ischaemic stroke, in addition to medical therapy, compared to medical therapy alone, improve functional outcome at 90 days?

PRECISE

30 June 2017 Fraser Magee Emergency Medicine Leave a comment

In patients with moderate-to-severe sciatica, does pregabalin compared to placebo reduce leg pain?

HYBERNATUS

13 January 2017 Adrian Wong Intensive Care Medicine 2 comments

In patients with convulsive status epilepticus, does the addition of therapeutic hypothermia to standard care improve neurological outcomes?

POCUS: Moretti

15 November 2016 David Slessor Emergency Medicine, Intensive Care Medicine Leave a comment

In mechanically ventilated patients with subarachnoid hemorrhage (SAH), does the distensibility of IVC on ultrasound, predict fluid responsiveness measured by thermodilution?

PATCH

23 September 2016 David Slessor Emergency Medicine, Intensive Care Medicine 2 comments

In patients with acute intracerebral haemorrhage, associated with antiplatelet therapy, does platelet transfusion compared with standard care reduce death or dependence?

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