Month: November 2024

Quetiapine Versus Haloperidol for Delirium

22 November 2024 Hrishee Vaidya Intensive Care Medicine, Summaries Leave a comment

Quetiapine Versus Haloperidol in the Management of Hyperactive Delirium: Randomized Controlled Trial Zakhary et al. Neurocritical Care; Oct;41(2):550-557. doi:10.1007/s12028-024-01948-w Clinical Question In critically ill patients with delirium, does quetiapine in comparison to haloperidol, reduce the severity of delirium? Background Delirium affects 30-50% of adult ICU patients Haloperidol is licensed for the treatment of acute delirium in the UK Previous RCTs […]

Pupillometry Thresholds for Neuroprognostication

22 November 2024 stephen.waite2@nhs.scot Intensive Care Medicine, Summaries Leave a comment

Validating quantitative pupillometry thresholds for neuroprognostication after out‑of‑hospital cardiac arrest. A predefined substudy of the Blood Pressure and Oxygenations Targets After Cardiac Arrest (BOX)‑trial Nyholm. Intensive Care Med 2024; 50:1484–1495. doi.org/10.1007/s00134-024-07574-6 Clinical Question In adult out-of-hospital cardiac arrest (OHCA) survivors of presumed cardiac cause who are comatose post-admission, do automated pupillometry thresholds of quantitatively assessed pupillary light reflex (qPLR) < […]

Flexible vs Restrictive Visiting in the ICU

22 November 2024 Roland Amoah Intensive Care Medicine, Summaries Leave a comment

Long-term effects of flexible visitation in the intensive care unit on family members’ mental health: 12-month results from a randomized clinical trial JMB de Souza et al. Intensive Care Med (2024); 50:1614–1621. DOI: 10.1007/s00134-024-07577-3 Clinical Question In family members of intensive care patients, does a flexible visiting policy, compared to a restrictive one, improve the prevalence of depression, anxiety and […]