PARTNER
For surrogate decision makers of critically ill patients, does a multi-component family support intervention impact on the surrogates’ hospital anxiety and depression scale (HADS) at 6 months?
Continue reading »Author: Celia Bradford
IOTA
In patients with sepsis, critical illness, stroke, trauma, myocardial infarction, cardiac arrest and those who had emergency surgery does a liberal oxygen strategy compared with a conservative oxygen strategy increase hospital mortality?
Continue reading »SMART
In critically ill patients does the administration of balanced crystalloids compared with saline, reduce a 30 day composite outcome of death, new renal replacement therapy or persistent renal dysfunction?
Continue reading »ELAIN FOLLOW-UP
In adult critically ill patients, with acute kidney injury, does early initiation of RRT compared to delayed initiation of RRT reduce the composite endpoint of MAKE365; consisting of death, RRT and persistent renal dysfunction at one year?
Continue reading »TRICS-III
In patients undergoing cardiac surgery, who have a moderate-to-high risk of death, does a restrictive transfusion strategy compared with a liberal strategy impact on a composite outcome of death, myocardial infarction, stroke and acute kidney injury requiring dialysis
Continue reading »TRANSFUSE
In critically ill patients requiring transfusion, does the transfusion of the freshest available red cells compared to standard care impact on patient mortality?
Continue reading »SPARK
In critically ill patients, with mild renal failure, does furosemide infusion compared to placebo worsen kidney function?
Continue reading »ATHOS-3
In patients with refractory vasodilatory shock does the addition of angiotensin II improve blood pressure compared with standard vasopressor therapy?
Continue reading »LEVO-CTS
In patients with LVEF <35% undergoing cardiac surgery does levosimenden compared with placebo reduce the incidence of a composite outcome of: death at day 30; renal replacement therapy at day 30; perioperative myocardial infarct at day 5; and use of mechanical assist device at day 5
Continue reading »AMACING
In high-risk patients receiving contrast medium, does prophylactic hydration with normal saline compared to no prophylaxis impact the rate of contrast-induced nephropathy?
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