Steve Mathieu

Steve is a Clinical Director and Consultant in Intensive Care and Anaesthesia at Queen Alexandra Hospital, Portsmouth, UK. He is co-editor of the The Bottom Line and ICM Case Summaries. He also has developed and maintains the Wessex ICS and Portsmouth ICU sites. He is a Faculty Tutor for Intensive Care training and Council member of the Intensive Care Society. His interests include medical education, information technology and patient and relative experience. @stevemathieu75

AIRWAYS-2

In adult patients with non-traumatic out-of-hospital cardiac arrest, does a supraglottic airway device compared with tracheal intubation as the initial advanced airway management strategy, improve functional neurological outcome?

BICAR-ICU

22 June 2018 Steve Mathieu Intensive Care Medicine 5 comments

In critically ill patients with severe metabolic acidaemia (pH ≤7⋅20), does the infusion of sodium bicarbonate, compared with no infusion, to reach and maintain a targeted pH of 7⋅30 decrease the primary composite outcome of mortality by day 28 or the presence of at least one organ failure at day 7?

RELIEF

18 May 2018 Steve Mathieu Intensive Care Medicine, Peri-operative Medicine, Summaries 5 comments

In adult patients undergoing major elective abdominal surgery, does a restrictive fluid regimen compared with a liberal fluid regimen reduce complications and improved disability-free survival?

Steroids in Sepsis

5 January 2018 Steve Mathieu Blog, Editorial 4 comments

In patients with septic shock, do corticosteroids compared to placebo reduce mortality?
This is an editorial blog post in anticipation of the ADRENAL trial results to be presented at #CCR18.

EPICC

18 August 2017 Steve Mathieu Intensive Care Medicine Leave a comment

Intensive versus standard physical rehabilitation therapy in the critically ill (EPICC): a multicentre, parallel-group, randomised controlled trial Wright. 2017. Thorax 2017: 0:1–9. doi:10.1136/thoraxjnl-2016-209858 Clinical Question Does an increased intensity of ICU based physical rehabilitation therapy improve improve long-term physical quality of life compared with a standard intensity of physical rehabilitation? Background Physical and psychological recovery after a period of critical […]

P-Value

30 July 2017 Steve Mathieu Evidence-based Medicine One comment

P-values – interpreting the evidence series

Kentish-Barnes

7 July 2017 Steve Mathieu Intensive Care Medicine One comment

Among relatives who died in the Intensive Care Unit (ICU), does a condolence letter from a clinician, compared to no condolence letter, effect grief symptoms?

Detsky

16 June 2017 Steve Mathieu Intensive Care Medicine Leave a comment

What is the discriminative accuracy of physicians and nurses in predicting 6-month mortality and functional outcomes of critically ill patients?

Critical Appraisal – Glossary

27 May 2017 Steve Mathieu Evidence-based Medicine Leave a comment

Rather than reinvent the wheel, we are delighted to include a link to the RCEM Critical Appraisal Dictionary. The RCEM learning site provides excellent open access educational resources, including critical care appraisal modules

Type 1 and 2 Errors

19 May 2017 Steve Mathieu Evidence-based Medicine Leave a comment

In statistical hypothesis testing, a type I error is the incorrect rejection of a true null hypothesis (a “false positive”), while a type II error is incorrectly retaining a false null hypothesis (a “false negative”). The more you try and avoid a Type I error (false positive), the more likely a Type II error (false negative) may happen. Researchers have found that an alpha level of 5% is a good balance between these two issues

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