A compendium of critical appraisals in Intensive Care Medicine research and related specialties
A collection of TBL summaries relevant to Emergency Medicine
In trauma patients with or at risk of significant haemorrhage, does the early administration of a short course of tranexamic acid (TXA) affect the mortality, incidence of occlusive events and the amount of blood transfused?
Continue reading »In patients with suspected acute coronary syndrome (ACS) does a novel accelerated diagnostic protocol (ADP) identify low risk patients suitable for discharge after a single high-sensitivity troponin T (hs-cTnT)?
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In patients with severe trauma and predicted to require massive transfusion, does the use of a transfusion protocol using a 1:1:1 ratio of plasma to platelets to red blood cells (RBCs) compared to 1:1:2 improve mortality?
Continue reading »In patients who are in refractory cardiac arrest, does protocolised management involving mechanical CPR, Hypothermia, ECMO and early reperfusion improve survival rate?
Continue reading »In patients with refractory ventricular fibrillation does the use of esmolol improve mortality?
Continue reading »In patients with septic shock, does Activated Protein C (also known as drotrecogin alfa or DrotAA) compared with placebo reduce mortality?
Continue reading »In patients who require emergency intubation and are not tolerating pre-oxygenation, does the use of ‘delayed sequence intubation’ (DSI) improve pre-intubation oxygen saturations (SpO2)?
Continue reading »Does the application of cricoid pressure during induction of anaesthesia control the regurgitation and pulmonary aspiration of gastric or oesophageal contents?
Continue reading »In obese patients with simulated difficult laryngoscopy, does the use of nasal oxygen prolong the duration that oxygen saturations remain ≥95%?
Continue reading »In critically ill adults, does a single induction dose of etomidate compared to ketamine affect organ failure scores during the subsequent first 3 days?
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