LeoPARDS
In adult patients who have sepsis, does levosimendan reduce the incidence and severity of acute organ dysfunction compared with placebo?
Continue reading »Category: Intensive Care Medicine
A collection of TBL summaries relevant to Intensive Care Medicine
CLASSIC
In ICU patients with septic shock who have had initial fluid resuscitation, what are the effects and feasibility of a protocol restricting further resuscitation fluid as opposed to standard care?
Continue reading »PATCH
In patients with acute intracerebral haemorrhage, associated with antiplatelet therapy, does platelet transfusion compared with standard care reduce death or dependence?
Continue reading »van Lieshout
In critically ill patients requiring interhospital ground transport, is a nurse-led transfer team non-inferior to a physician-led team, for the proportion of patients with critical events?
Continue reading »RESCUEicp
In patients with a traumatic brain injury (TBI) and refractory intracranial hypertension, does decompressive craniectomy, result in more favourable mortality and neurological outcomes at 6 months, compared with barbiturate coma and continued medical management?
Continue reading »Philpot
Do observers of simulated family conversations discussing organ donation respond more favourably to the discussion if it contains extra information about the benefits of donation compared to a standard conversation?
Continue reading »Morris
In patients with acute respiratory failure, does early delivery of a standardised ICU and hospital rehabilitation programme improve physical function and reduce hospital length of stay?
Continue reading »VASST
In adult patients with septic shock, does the addition of vasopressin infusion to a norepinephrine infusion compared to a norepinephrine infusion alone decrease mortality rate at 28 days?
Continue reading »VANISH Trial
Does early vasopressin use reduce the risk of kidney failure in patients with septic shock compared with norepinephrine?
Continue reading »HOT-ER
In hypoxic adults presenting to the emergency department, does nasal high-flow oxygen compared to standard oxygen therapy reduce the need for advanced respiratory support?
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