BLING2
In adult ICU patients on beta-lactam antibiotics, does continuous infusion compared to intermittent bolus increase survival?
Continue reading »Category: Intensive Care Medicine
A collection of TBL summaries relevant to Intensive Care Medicine
AVOID
In patients with ST-elevation-myocardial infarction (STEMI), without hypoxia, does receiving supplemental oxygen compared with no supplemental oxygen reduce early myocardial injury?
Continue reading »REVERT
Does a modified Valsalva technique, incorporating a leg lift procedure, result in improved success in converting a supraventricular tachycardia to sinus rhythm in patients presenting to the Emergency Department?
Continue reading »Idarucizumab for Dabigatran Reversal
In patients taking dabigatran, who present with serious bleeding or require urgent surgery/intervention is idarucizumab safe and efficacious for the reversal of anticoagulation?
Continue reading »THAPCA-OH
In children suffering an out-of-hospital cardiac arrest, does hypothermia compared to normothermia increase survival with a good neurobehavioural outcome?
Continue reading »Niemann
In organ donors, following diagnosis of brainstem death, does therapeutic hypothermia decrease delayed graft function in kidney recipients?
Continue reading »PermiT
In critically ill adults, does restriction of non-protein calories (permissive underfeeding) compared to standard feeding reduce mortality at 90 days?
Continue reading »Freemantle
Do patients admitted to English NHS hospitals on weekend days, compared to those admitted during week days, have an increased 30-day mortality?
Continue reading »ABLE
In critically ill patients requiring blood, does transfusion with “fresh” RBC’s (stored for 8 days or less) compared with standard issue RBCs (stored 2-42 days) reduce 90 day mortality?
Continue reading »SHOCK 2
Intra-aortic balloon counterpulsation in acute myocardial infarction complicated by cardiogenic shock (IABP-SHOCK II): final 12 month results of a randomised, open-label trial IABP-SHOCK II Trial Investigators.NEJM;2012,367(14)1287-96, DOI: 10.1056/NEJMoa1208410 Clinical Question In patients with acute MI and cardiogenic shock, does intraaortic balloon counterpulsation (IABP) vs. medical therapy alone improve mortality? Design Randomised controlled trial Randomisation performed centrally via internet based program […]
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