CESAR
Is extracorporeal membrane oxygenation (ECMO) a safe, efficacious and cost-effective treatment compared with conventional ventilation for the management of severe adult respiratory failure?
Continue reading »Category: Intensive Care Medicine
A collection of TBL summaries relevant to Intensive Care Medicine
Chatterjee
In patients with PE, does the addition of thrombolysis to anticoagulation, compared with anticoagulation alone, affect mortality and bleeding complications?
Continue reading »TOPCOAT
In patients with submassive PE, does the use of tenecteplase + heparin, compared to heparin alone, improve patient orientated outcomes?
Continue reading »PEITHO
In patients with intermediate-risk/sub-massive pulmonary embolism (PE), does the addition of tenecteplase, compared with heparin alone improve the composite outcome of death and haemodynamic decompensation?
Continue reading »MOPETT
In patients with moderate Pulmonary Embolism (PE), does low dose thrombolysis + anticoagulation, compared with anticoagulation alone, reduce pulmonary artery pressure at 28 months?
Continue reading »MAPPETT 3
In patients with sub-massive PE, does the use of thrombolysis + heparin, compared to heparin alone, reduce the composite outcome of mortality or clinical deterioration?
Continue reading »SEPSISPAM
In patients with septic shock does a high target mean arterial pressure (MAP), compared to a low target MAP, improve mortality?
Continue reading »NICE-SUGAR
In critically ill adults that are expected to be in Intensive Care for 3 days or more, does intensively controlled blood glucose compared to conventionally controlled blood glucose reduce mortality at 90 days?
Continue reading »CORTICUS
In adult patients with severe septic shock, does hydrocortisone versus placebo reduce mortality at 28 days?
Continue reading »OSCILLATE
Does High Frequency Oscillatory Ventilation (HFOV) improve mortality in patients with new onset moderate-severe ARDS compared with standard ventilation?
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