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In critically ill patients requiring blood, does transfusion with “fresh” RBC’s (stored for 8 days or less) compared with standard issue RBCs (stored 2-42 days) reduce 90 day mortality?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
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In critically ill patients requiring blood, does transfusion with “fresh” RBC’s (stored for 8 days or less) compared with standard issue RBCs (stored 2-42 days) reduce 90 day mortality?
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Intra-aortic balloon counterpulsation in acute myocardial infarction complicated by cardiogenic shock (IABP-SHOCK II): final 12 month results of a randomised, open-label trial IABP-SHOCK II Trial Investigators.NEJM;2012,367(14)1287-96, DOI: 10.1056/NEJMoa1208410 Clinical Question In patients with acute MI and cardiogenic shock, does intraaortic balloon counterpulsation (IABP) vs. medical therapy alone improve mortality? Design Randomised controlled trial Randomisation performed centrally via internet based program […]
Continue reading »Does the administration of paracetamol reduce mortality in critically ill patients on the Intensive Care Unit?
Continue reading »In patients who are administered vasopressor medication intravenously, what are the published reports on local tissue injury and extravasation?
Continue reading »In patients with severe traumatic brain injury does monitoring intracranial pressure improve mortality and improve neurological function?
Continue reading »In paediatric patients with severe febrile illnesses, in a resource limited setting, do fluid boluses with albumin vs. saline vs. no fluid boluses affect mortality?
Continue reading »What is the clinical outcome of patients after major non-cardiac surgery in Europe?
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In patients with severe pancreatitis, does early enteral feeding compared with on-demand feeding reduce death or major infection?
Continue reading »In older patients with malignant middle cerebral artery infarction does early hemicraniectomy, compared with standard care, improve survival without severe disability?
Continue reading »In patients with acute hypoxaemic respiratory failure, does high-flow oxygen through nasal cannula, compared with standard oxygen delivered through a facemask or non-invasive positive-pressure ventilation, prevent intubation?
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