PROWESS-SHOCK
In patients with septic shock, does Activated Protein C (also known as drotrecogin alfa or DrotAA) compared with placebo reduce mortality?
Continue reading »Category: Summaries
A category to collect all the summaries, so that they can be used in menus and widgets. Please don’t expand this – “Specialties” and “Special Topics” have been created as a custom category sets for the clinical topics.
Weingart
In patients who require emergency intubation and are not tolerating pre-oxygenation, does the use of ‘delayed sequence intubation’ (DSI) improve pre-intubation oxygen saturations (SpO2)?
Continue reading »Sellick
Does the application of cricoid pressure during induction of anaesthesia control the regurgitation and pulmonary aspiration of gastric or oesophageal contents?
Continue reading »Ramachandran
In obese patients with simulated difficult laryngoscopy, does the use of nasal oxygen prolong the duration that oxygen saturations remain ≥95%?
Continue reading »KETASED
In critically ill adults, does a single induction dose of etomidate compared to ketamine affect organ failure scores during the subsequent first 3 days?
Continue reading »Yeatts
In adults requiring emergency intubation, does video laryngoscopy (VL) compared to direct laryngoscopy (DL) lead to better or worse in-hospital mortality?
Continue reading »McCourt
In patients undergoing rapid sequence induction, does the use of suxamethonium or rocuronium (at a standard or higher dose), produce better intubating conditions?
Continue reading »ARF Trial Network
In critically ill patients with acute kidney injury (AKI) does intensive compared with ‘less intensive’ renal-replacement therapy (RRT) improve mortality?
Continue reading »MIDEX-PRODEX
In adult intensive care patients requiring mechanical ventilation, is dexmedetomidine inferior to propofol or midazolam in achieving target sedation level?
Continue reading »TRISS
In patients with septic shock, does blood transfusion at a lower or higher haemoglobin threshold improve mortality?
Continue reading »