DESTINY II
In older patients with malignant middle cerebral artery infarction does early hemicraniectomy, compared with standard care, improve survival without severe disability?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
A category to collect all the summaries, so that they can be used in menus and widgets. Please don’t expand this – “Specialties” and “Special Topics” have been created as a custom category sets for the clinical topics.
In older patients with malignant middle cerebral artery infarction does early hemicraniectomy, compared with standard care, improve survival without severe disability?
Continue reading »In patients with acute hypoxaemic respiratory failure, does high-flow oxygen through nasal cannula, compared with standard oxygen delivered through a facemask or non-invasive positive-pressure ventilation, prevent intubation?
Continue reading »In pre-hospital trauma patients undergoing rapid sequence intubation (RSI), does fentanyl-ketamine-rocuronium induction compared to etomidate-suxamethonium induction affect intubation success or haemodynamic responses to laryngoscopy?
Continue reading »In adult patients with alcoholic hepatitis, does prednisolone and / or pentoxifylline compared to placebo reduce mortality?
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In patients with septic shock, what is the relationship between appropriateness of initial empiric antimicrobial therapy and survival?
Continue reading »Does High-flow therapy by nasal cannula (HFNC) improve the efficiency of preoxygenation before intubation compared with a high fraction-inspired oxygen facial mask (HFFM)
Continue reading »In adult patients with sepsis, severe sepsis or septic shock, is a single dose of etomidate for induction of anaesthesia, compared with any other induction, associated with a difference in mortality?
Continue reading »In patients treated with therapeutic hypothermia following cardiac arrest, can clinical examination, neuronspecific enolase (NSE), and median nerve somatosensory-evoked potentials (SEPs) predict poor outcome?
Continue reading »In adults undergoing cardiac surgery, does a restrictive transfusion strategy (Hb > 75 g/l) compared to a liberal transfusion strategy (Hb > 90 g/l) lead to fewer infections and ischaemic events within 3 months?
Continue reading »In patients with out-of-hospital (OOH) cardiac arrest does a target temperature management (TTM) of 33°C vs. 36°C improve cognitive function
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