Ferrer
In patients with severe sepsis or septic shock, is the timing of first administration of antibiotics associated with the in-hospital mortality rate?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
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In patients with severe sepsis or septic shock, is the timing of first administration of antibiotics associated with the in-hospital mortality rate?
Continue reading »Does a delay in antibiotic administration in patients with septic shock result in an increased mortality?
Continue reading »Does intravenous or nebulised MgSO4 improve symptoms of breathlessness and reduce the need for hospital admission in adults with severe acute asthma?
Continue reading »In adult patients undergoing mechanical ventilation, does a strategy involving no continuous sedation, compared to a strategy of continuous sedation by infusion with a daily interruption, reduce the number of days of mechanical ventilation in the first 4 weeks?
Continue reading »In patients with septic shock, is mortality affected by the use of adrenaline (epinephrine) alone in comparison to noradrenaline ± dobutamine?
Continue reading »Is extracorporeal membrane oxygenation (ECMO) a safe, efficacious and cost-effective treatment compared with conventional ventilation for the management of severe adult respiratory failure?
Continue reading »In patients with PE, does the addition of thrombolysis to anticoagulation, compared with anticoagulation alone, affect mortality and bleeding complications?
Continue reading »In patients with submassive PE, does the use of tenecteplase + heparin, compared to heparin alone, improve patient orientated outcomes?
Continue reading »In patients with intermediate-risk/sub-massive pulmonary embolism (PE), does the addition of tenecteplase, compared with heparin alone improve the composite outcome of death and haemodynamic decompensation?
Continue reading »In patients with moderate Pulmonary Embolism (PE), does low dose thrombolysis + anticoagulation, compared with anticoagulation alone, reduce pulmonary artery pressure at 28 months?
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