Idarucizumab for Dabigatran Reversal
In patients taking dabigatran, who present with serious bleeding or require urgent surgery/intervention is idarucizumab safe and efficacious for the reversal of anticoagulation?
Continue reading »Category: Peri-operative Medicine
A collection of TBL summaries relevant to Peri-operative Medicine
BRIDGE Study
In elective surgical patients with atrial fibrillation who are suspending their normal warfarin peri-operatively, does no bridging anticoagulation compared to bridging anticoagulation with dalteparin increase the incidence of thromboembolism or reduce the incidence of major bleeding?
Continue reading »Freemantle
Do patients admitted to English NHS hospitals on weekend days, compared to those admitted during week days, have an increased 30-day mortality?
Continue reading »STOP-IT
In patients with intraabdominal sepsis and who have received adequate source control, does a fixed short course of antibiotics result in similar treatment success compared to a longer duration of antibiotic therapy?
Continue reading »Loubani
In patients who are administered vasopressor medication intravenously, what are the published reports on local tissue injury and extravasation?
Continue reading »EUSOS
What is the clinical outcome of patients after major non-cardiac surgery in Europe?
Continue reading »PREOXYFLOW
Does High-flow therapy by nasal cannula (HFNC) improve the efficiency of preoxygenation before intubation compared with a high fraction-inspired oxygen facial mask (HFFM)
Continue reading »Gu
In adult patients with sepsis, severe sepsis or septic shock, is a single dose of etomidate for induction of anaesthesia, compared with any other induction, associated with a difference in mortality?
Continue reading »TITRe2
In adults undergoing cardiac surgery, does a restrictive transfusion strategy (Hb > 75 g/l) compared to a liberal transfusion strategy (Hb > 90 g/l) lead to fewer infections and ischaemic events within 3 months?
Continue reading »CRASH-2
In trauma patients with or at risk of significant haemorrhage, does the early administration of a short course of tranexamic acid (TXA) affect the mortality, incidence of occlusive events and the amount of blood transfused?
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