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In adult ICU patients on beta-lactam antibiotics, does continuous infusion compared to intermittent bolus increase survival?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
These are summaries of trials published in 2015.
In adult ICU patients on beta-lactam antibiotics, does continuous infusion compared to intermittent bolus increase survival?
Continue reading »In patients with ST-elevation-myocardial infarction (STEMI), without hypoxia, does receiving supplemental oxygen compared with no supplemental oxygen reduce early myocardial injury?
Continue reading »In patient with acute, moderate to severe pain in the ED, does ketamine compared with morphine, reduce pain scores by an equivalent amount?
Continue reading »Does a modified Valsalva technique, incorporating a leg lift procedure, result in improved success in converting a supraventricular tachycardia to sinus rhythm in patients presenting to the Emergency Department?
Continue reading »In patients taking dabigatran, who present with serious bleeding or require urgent surgery/intervention is idarucizumab safe and efficacious for the reversal of anticoagulation?
Continue reading »In children suffering an out-of-hospital cardiac arrest, does hypothermia compared to normothermia increase survival with a good neurobehavioural outcome?
Continue reading »In elective surgical patients with atrial fibrillation who are suspending their normal warfarin peri-operatively, does no bridging anticoagulation compared to bridging anticoagulation with dalteparin increase the incidence of thromboembolism or reduce the incidence of major bleeding?
Continue reading »In organ donors, following diagnosis of brainstem death, does therapeutic hypothermia decrease delayed graft function in kidney recipients?
Continue reading »In critically ill adults, does restriction of non-protein calories (permissive underfeeding) compared to standard feeding reduce mortality at 90 days?
Continue reading »In patients with intraabdominal sepsis and who have received adequate source control, does a fixed short course of antibiotics result in similar treatment success compared to a longer duration of antibiotic therapy?
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