Year: 2015

These are summaries of trials published in 2015.

ABLE

17 July 2015 Steve Mathieu Intensive Care Medicine One comment

In critically ill patients requiring blood, does transfusion with “fresh” RBC’s (stored for 8 days or less) compared with standard issue RBCs (stored 2-42 days) reduce 90 day mortality?

Suzuki

3 July 2015 Steve Mathieu Intensive Care Medicine Leave a comment

Does the administration of paracetamol reduce mortality in critically ill patients on the Intensive Care Unit?

Loubani

In patients who are administered vasopressor medication intravenously, what are the published reports on local tissue injury and extravasation?

FLORALI

29 May 2015 Steve Mathieu Intensive Care Medicine 3 comments

In patients with acute hypoxaemic respiratory failure, does high-flow oxygen through nasal cannula, compared with standard oxygen delivered through a facemask or non-invasive positive-pressure ventilation, prevent intubation?

Lyon

22 May 2015 Duncan Chambler Emergency Medicine Leave a comment

In pre-hospital trauma patients undergoing rapid sequence intubation (RSI), does fentanyl-ketamine-rocuronium induction compared to etomidate-suxamethonium induction affect intubation success or haemodynamic responses to laryngoscopy?

STOPAH

15 May 2015 Duncan Chambler Intensive Care Medicine Leave a comment

In adult patients with alcoholic hepatitis, does prednisolone and / or pentoxifylline compared to placebo reduce mortality?

PREOXYFLOW

1 May 2015 Steve Mathieu Emergency Medicine, Intensive Care Medicine, Peri-operative Medicine One comment

Does High-flow therapy by nasal cannula (HFNC) improve the efficiency of preoxygenation before intubation compared with a high fraction-inspired oxygen facial mask (HFFM)

Gu

24 April 2015 Duncan Chambler Emergency Medicine, Intensive Care Medicine, Peri-operative Medicine Leave a comment

In adult patients with sepsis, severe sepsis or septic shock, is a single dose of etomidate for induction of anaesthesia, compared with any other induction, associated with a difference in mortality?

TITRe2

10 April 2015 Duncan Chambler Intensive Care Medicine, Peri-operative Medicine Leave a comment

In adults undergoing cardiac surgery, does a restrictive transfusion strategy (Hb > 75 g/l) compared to a liberal transfusion strategy (Hb > 90 g/l) lead to fewer infections and ischaemic events within 3 months?

Lilja

3 April 2015 David Slessor Emergency Medicine, Intensive Care Medicine Leave a comment

In patients with out-of-hospital (OOH) cardiac arrest does a target temperature management (TTM) of 33°C vs. 36°C improve cognitive function

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