P-Value
P-values – interpreting the evidence series
Continue reading »Search Results for: Sepsis
Corl
In fluid responsive spontaneously breathing critically unwell patients undergoing resuscitation, does the collapsibility of the inferior vena cava (cIVC), as determined by point of care ultrasound (POCUS), when compared to administering a fluid bolus predict a >10% increase in cardiac output?
Continue reading »Detsky
What is the discriminative accuracy of physicians and nurses in predicting 6-month mortality and functional outcomes of critically ill patients?
Continue reading »ATHOS-3
In patients with refractory vasodilatory shock does the addition of angiotensin II improve blood pressure compared with standard vasopressor therapy?
Continue reading »INSTINCT
In patients with necrotising soft tissue infection (NSTI), does the use of intravenous immunoglobulin (IVIG) compared to placebo improve patient reported physical outcomes?
Continue reading »EMPIRICUS
In non-neutropenic critically ill patients with sepsis, multiple Candida colonisation, and multiple organ failure exposed to broad-spectrum antibacterials, does empirical micafungin therapy compared to placebo increase invasive fungal infection-free survival at day 28?
Continue reading »WOMAN Trial
Does the early administration of tranexamic acid (TXA), compared with placebo, reduce death from bleeding in women with post-partum haemorrhage (PPH)?
Continue reading »DESIRE
In ventilated patients with sepsis, does a sedation strategy with dexmedetomidine compared with no dexmedetomidine improve mortality and number of ventilator-free days?
Continue reading »Choudhury
In patients with cirrhosis and septic shock does terlipressin in comparison with noradrenaline improve haemodynamic parameters?
Continue reading »El Adawi
In adult patients with severe sepsis, does methylene blue compared to vasopressin reduce noradrenaline requirement and increase blood pressure?
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