CASS
In septic and mechanically ventilated patients aged 50 or over, does 24 hours of induced hypothermia followed by 48 hours of normothermia improve 30-day mortality compared to routine care?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
In septic and mechanically ventilated patients aged 50 or over, does 24 hours of induced hypothermia followed by 48 hours of normothermia improve 30-day mortality compared to routine care?
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In adult patients undergoing major elective abdominal surgery, does a restrictive fluid regimen compared with a liberal fluid regimen reduce complications and improved disability-free survival?
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In patients with status epilepticus (SE) and cluster attacks of seizures, (CS) does IV levetiracetam vs. IV phenytoin improve rate of control of seizures?
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In critically ill adults, does the administration of ramelteon compared to placebo reduce the length of intensive care stay?
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In post-operative patients requiring mechanical ventilation, does intensive insulin therapy compared to conventional insulin therapy reduce mortality?
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In critically ill patients with septic shock, does the combination of hydrocortisone plus fludrocortisone therapy reduce 90 day mortality?
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In critically ill adult patients, does late supplemental parenteral nutrition (PN), compared with early PN reduce the duration of dependency on intensive care?
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In critically ill patients does the administration of balanced crystalloids compared with saline, reduce a 30 day composite outcome of death, new renal replacement therapy or persistent renal dysfunction?
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In adult critically ill patients, with acute kidney injury, does early initiation of RRT compared to delayed initiation of RRT reduce the composite endpoint of MAKE365; consisting of death, RRT and persistent renal dysfunction at one year?
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In critically ill patients with septic shock, does hydrocortisone compared with placebo, reduce 90 day mortality?
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