Marik
Does intravenous vitamin C, hydrocortisone and thiamine in addition to standard treatment, improve mortality in ICU patients with severe sepsis or septic shock, compared with standard treatment alone?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
Does intravenous vitamin C, hydrocortisone and thiamine in addition to standard treatment, improve mortality in ICU patients with severe sepsis or septic shock, compared with standard treatment alone?
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All of us on the editorial team would like to wish our subscribers, followers and readers our very best wishes for this festive season and the year ahead.
We’re taking our usual two week break, and we shall return in 2017 with more #FOAMed.
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In critically ill adults requiring renal replacement therapy, does higher intensity dialysis compared to lower intensity dialysis reduce mortality?
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In critically ill patients who are anaemic, does early administration of intravenous iron compared to placebo reduce the requirement for blood transfusion?
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In patients undergoing internal jugular cannulation under ultrasound guidance, does the use of an oblique compared to short- and long-axis approach increase success rate and decrease complications?
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In patients with severe sepsis does hydrocortisone compared to placebo prevent the development of septic shock?
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In adult patients who have sepsis, does levosimendan reduce the incidence and severity of acute organ dysfunction compared with placebo?
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In ICU patients with septic shock who have had initial fluid resuscitation, what are the effects and feasibility of a protocol restricting further resuscitation fluid as opposed to standard care?
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Does early vasopressin use reduce the risk of kidney failure in patients with septic shock compared with norepinephrine?
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Keeping up to date with the medical literature – Dave Slessor
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