COIITSS
In patients with septic shock who are treated with corticosteroids, does tight glycaemic control (4.44–6.1 mmol/l) compared with less-tight glycaemic control (<8.3 mmol/l) reduce in-hospital mortality?
Continue reading »Search Results for: Sepsis
TBL Top 10 for 2017
It’s been another big year for research in ICM, EM and Peri-operative Care. What do the TBL editors think are the best trials of 2017?
Continue reading »MoDUS
In mechanically ventilated patients, does the early administration of simvastatin compared to placebo reduce the incidence of brain dysfunction (delirium and / or coma)?
Continue reading »SSSP2
In Zambian adults with sepsis and hypotension, does a resuscitation protocol implemented early after presentation to the Emergency Department improve in-hospital mortality compared with usual care?
Continue reading »CHECK-UP Position
In critically ill patients undergoing emergency intubation, does the ramped position compared to sniffing position reduce the incidence of oxygen desaturation?
Continue reading »INPRESS
In high-risk patients undergoing surgical procedures, does a strategy of targeting individualised systolic blood pressure compared to standard practice reduce organ dysfunction
Continue reading »Seymour
In patients with severe sepsis or septic shock, does a faster time to completion of a 3 hour bundle of care, compared with a slower time, affect in hospital mortality?
Continue reading »POISE 1
In patients undergoing non-cardiac surgery, do beta-blockers compared to placebo reduce the composite of death, MI or non-fatal cardiac arrest?
Continue reading »SHENFU
In patients with in-hospital cardiac arrest, does Shenfu (a traditional Chinese
medicine), improve 28 day mortality?
SPARK
In critically ill patients, with mild renal failure, does furosemide infusion compared to placebo worsen kidney function?
Continue reading »