EPaNIC
In critically ill adult patients, does late supplemental parenteral nutrition (PN), compared with early PN reduce the duration of dependency on intensive care?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
A collection of TBL summaries relevant to Intensive Care Medicine
In critically ill adult patients, does late supplemental parenteral nutrition (PN), compared with early PN reduce the duration of dependency on intensive care?
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In non-critically ill adult patients admitted to hospital from the Emergency Department, does the administration of a balanced salt solution compared with normal saline, reduce hospital free days to day 28?
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In critically ill patients does the administration of balanced crystalloids compared with saline, reduce a 30 day composite outcome of death, new renal replacement therapy or persistent renal dysfunction?
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For healthcare professionals interpreting chest radiographs, does an educational intervention compared to no educational intervention improve the diagnosis or exclusion of acute respiratory distress syndrome (ARDS)
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In adult critically ill patients, with acute kidney injury, does early initiation of RRT compared to delayed initiation of RRT reduce the composite endpoint of MAKE365; consisting of death, RRT and persistent renal dysfunction at one year?
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In patients who are unplanned admissions to critical care, does the day and time of admission to critical care influence acute hospital mortality?
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In mechanically ventilated patients with ARDS, does airway pressure release ventilation (APRV) compared to conventional low tidal volume ventilation (LTV) reduce duration of mechanical ventilation?
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In critically ill patients with septic shock, does hydrocortisone compared with placebo, reduce 90 day mortality?
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In patients with septic shock who are treated with corticosteroids, does tight glycaemic control (4.44–6.1 mmol/l) compared with less-tight glycaemic control (<8.3 mmol/l) reduce in-hospital mortality?
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In patients with moderate to severe acute respiratory distress syndrome (ARDS) does use of a lung recruitment maneuver associated with positive end-expiratory pressure (PEEP) titration according to the best respiratory-system compliance, compared with a conventional low-PEEP strategy, decrease 28-day mortality?
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