MoDUS
In mechanically ventilated patients, does the early administration of simvastatin compared to placebo reduce the incidence of brain dysfunction (delirium and / or coma)?
Continue reading »Category: Intensive Care Medicine
A collection of TBL summaries relevant to Intensive Care Medicine
PRESERVE
In high-risk patients undergoing angiography, does the administration of bicarbonate and/or acetylcysteine, compared with placebo, prevent major adverse events and acute kidney injury?
Continue reading »TRICS-III
In patients undergoing cardiac surgery, who have a moderate-to-high risk of death, does a restrictive transfusion strategy compared with a liberal strategy impact on a composite outcome of death, myocardial infarction, stroke and acute kidney injury requiring dialysis
Continue reading »SSSP2
In Zambian adults with sepsis and hypotension, does a resuscitation protocol implemented early after presentation to the Emergency Department improve in-hospital mortality compared with usual care?
Continue reading »ICE-CUB 2
In critically ill patients aged over 75 years, does a recommendation for systematic ICU admission compared with standard care reduce 6 month mortality?
Continue reading »CHECK-UP Position
In critically ill patients undergoing emergency intubation, does the ramped position compared to sniffing position reduce the incidence of oxygen desaturation?
Continue reading »CHECK-UP Checklist
In critically ill patients undergoing intubation, does the use of a pre-intubation checklist compared to no checklist prevent oxygen desaturation or systolic hypotension?
Continue reading »EAT-ICU
In critically ill adult patients, does early goal-directed nutrition (EGDN) during ICU stay compared to standard care nutrition delivery result in improved physical quality of life at 6 months?
Continue reading »Reconnect
In critically ill adult patients who pass a spontaneous breathing trial (SBT), does 1-hour rest compared with immediate extubation reduce re-intubation rates at 48 hours?
Continue reading »TRANSFUSE
In critically ill patients requiring transfusion, does the transfusion of the freshest available red cells compared to standard care impact on patient mortality?
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