TOCIBRAS
In hospitalised adult patients with severe or critical COVID-19 pneumonia, does tocilizumab plus standard care compared with standard care alone, improve clinical outcomes at day 15?
Continue reading »Category: Summaries
A category to collect all the summaries, so that they can be used in menus and widgets. Please don’t expand this – “Specialties” and “Special Topics” have been created as a custom category sets for the clinical topics.
Dex-CSDH
In patients with chronic subdural haemorrhage, what effect does dexamethasone compared with placebo have on neurological outcome at 6 months?
Continue reading »PlasmAr
es convalescent plasma compared with placebo, improve patients’ clinical status at 30 days?
Continue reading »REMAP-CAP IL-6
In critically ill patients with COVID-19, do the IL-6 receptor antagonists, tocilizumab and sarilumab, compared with standard care, improve respiratory and cardiovascular organ support free days up to day 21?
Continue reading »BACC
In hospitalised patients with severe acute respiratory syndrome due to coronavirus 2 (SAR-CoV-2), does tocilizumab compared with placebo, reduce intubation rates or mortality?
Continue reading »DANMASK-19
In adults in Denmark reported to spend three hours or more outside of the home during the early stages of the COVID-19 pandemic, did a recommendation to wear a surgical face mask, compared with no recommendation to wear a surgical face mask, reduce SARS-CoV-2 infection at one month?
Continue reading »ARREST
In adults suffering out of hospital cardiac arrest (OHCA) presenting with an initial rhythm of VF or pulseless VT, does the implementation of early ECMO facilitated resuscitation compared to standard ACLS resuscitation improve survival to hospital discharge?
Continue reading »RECOVERY: COVID-19 Kaletra
In patients admitted to hospital with COVID-19, does Lopinavir-ritonavir therapy (Kaletra) compared to usual care, reduce 28-day mortality?
Continue reading »ITACTIC
In adult trauma patients presenting with signs of haemorrhagic shock does the utilisation of a viscoelastic haemostatic assay (VHA) augmented transfusion strategy compared to a strategy augmented by conventional coagulation tests (CCT) result in an increased number of patients alive and free of massive transfusion at 24 hours?
Continue reading »REDECAP
In conscious critically ill patients who have had a tracheostomy inserted as part of their ICU stay and have been weaned from mechanical ventilation, does an assessment of readiness for decannulation that is based on suctioning frequency, when compared to an assessment based on tracheostomy capping, result in a shorter time to successful decannulation?
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