A compendium of critical appraisals in Intensive Care Medicine research and related specialties
A category to collect all the summaries, so that they can be used in menus and widgets. Please don’t expand this – “Specialties” and “Special Topics” have been created as a custom category sets for the clinical topics.
In patients with atrial fibrillation (AF) on direct oral anticoagulant (DOAC) medications, does a standard approach to therapy interruption and resumption in the perioperative period result in an acceptable risk for bleeding and thromboembolic events?
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In trauma patients with hemorrhagic shock, does the use of low-dose arginine vasopressin compared to placebo reduce the volume of blood products transfused?
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In patients at high risk of respiratory complications after cardiac surgery, does the routine application of high-flow nasal oxygen compared to standard oxygen reduce hospital length of stay?
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Transfusion Volume for Children with Severe Anaemia in Africa K.Maitland. New England Journal of Medicine August 1st 2019; 381:5; 420-431. doi: 10.1056/NEJMoa1900100 Clinical Question In African children presenting to hospital with severe anaemia, is a blood transfusion volume of 30 ml/kg superior to 20 ml/kg in reducing 28 day mortality? Background Severe anaemia is a major cause of death and […]
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In children hospitalised with uncomplicated severe anaemia, is an immediate blood transfusion strategy superior to delayed transfusion in reducing 28-day mortality?
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In adults with decompensated heart failure who are at high-risk of diuretic resistance, does furosemide administered by infusion compared to intermittent bolus increase the incidence of freedom from congestion at 72 hours?
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In obese patients, does the use of recruitment maneuvers with high PEEP, compared with low PEEP, decrease postoperative pulmonary complications?
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In adult critically ill patients with hypoxemic respiratory failure necessitating intubation, does high-flow nasal cannula (HFNC) compared to bag-valve-mask (BVM) for both pre-oxygenation and oxygenation during intubation reduce desaturation?
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In patients with cirrhosis and acute variceal bleeding, does early transjugular intrahepatic portosystemic shunt (TIPS) compared to standard care increase transplant-free survival?
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In severely injured trauma patients, where anticoagulation is contraindicated, does the use of prophylactic inferior vena cava filters reduce the incidence of pulmonary embolism (PE)?
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