ABC Trial
In mechanically ventilated and sedated patients, do Spontaneous Awakening Trials (SAT) in addition to Spontaneous Breathing Trials (SBT) reduce dependence on mechanical ventilation?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
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In mechanically ventilated and sedated patients, do Spontaneous Awakening Trials (SAT) in addition to Spontaneous Breathing Trials (SBT) reduce dependence on mechanical ventilation?
Continue reading »In patients with acute kidney injury (AKI) and severe sepsis or septic shock, does extended daily haemofiltration (EDHF) compared with continuous venovenous haemofiltration (CVVHF) reduce time to renal recovery or mortality at 60 days?
Continue reading »Does the use of the short-acting β-blocker esmolol effectively control heart rate (HR) in patients with septic shock?
Continue reading »In patients with septic shock, does Activated Protein C (also known as drotrecogin alfa or DrotAA) compared with placebo reduce mortality?
Continue reading »In patients who require emergency intubation and are not tolerating pre-oxygenation, does the use of ‘delayed sequence intubation’ (DSI) improve pre-intubation oxygen saturations (SpO2)?
Continue reading »Does the application of cricoid pressure during induction of anaesthesia control the regurgitation and pulmonary aspiration of gastric or oesophageal contents?
Continue reading »In obese patients with simulated difficult laryngoscopy, does the use of nasal oxygen prolong the duration that oxygen saturations remain ≥95%?
Continue reading »In critically ill adults, does a single induction dose of etomidate compared to ketamine affect organ failure scores during the subsequent first 3 days?
Continue reading »In adults requiring emergency intubation, does video laryngoscopy (VL) compared to direct laryngoscopy (DL) lead to better or worse in-hospital mortality?
Continue reading »In patients undergoing rapid sequence induction, does the use of suxamethonium or rocuronium (at a standard or higher dose), produce better intubating conditions?
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