De Jonge
Does the use of Selective Decontamination of the Digestive Tract (SDD) affect ICU and hospital mortality and the acquisition of resistant organisms?
Continue reading »Category: Summaries
A category to collect all the summaries, so that they can be used in menus and widgets. Please don’t expand this – “Specialties” and “Special Topics” have been created as a custom category sets for the clinical topics.
HOPE-ICU
In critically ill patients does early treatment with haloperidol decrease the time that survivors spend in delirium or coma?
Continue reading »PAC-MAN
Pulmonary Artery Catheters in patient Management PAC-MAN study group, Lancet 2005;366;472-477 Clinical Question In critically ill patients, does the use of a pulmonary artery catheter (PAC) reduce mortality? Design Randomised controlled trial Non-blinded Stratified by age and presumptive clinical syndrome Intention to treat analysis Power calculation: 1281 patients would allow detection of a 10% change in absolute hospital mortality, with […]
Continue reading »CRASH-1
In adults with a head injury, do early corticosteroids compared to placebo reduce death and disability?
Continue reading »Meduri
Does a prolonged course of intravenous methylprednisolone improve lung function and reduce mortality in patients with unresolving ARDS
Continue reading »Annane
In patients with septic shock and relative adrenal deficiency does low dose corticosteroids improve 28 day mortality?
Continue reading »REDUCE
Is short-term (5 days) systemic glucocorticoid treatment in patients with COPD exacerbation as good as conventional (14 days) treatment in clinical outcome and does it decrease the overall exposure to steroids?
Continue reading »VSE
In patients in cardiac arrest, does vasopressin + epinephrine during CPR combined with steroid supplementation during and after CPR, improve survival to discharge with a good neurological outcome, in comparison to the use of epinephrine alone?
Continue reading »TracMan
In mechanically ventilated adult patients with a high risk of prolonged ventilation, does early tracheostomy compared with late tracheostomy reduce mortality at 30 days?
Continue reading »Bouderka
Does early tracheostomy reduce duration of mechanical ventilation and mortality in comparison with prolonged intubation in patients with head injury?
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