CORTICUS
In adult patients with severe septic shock, does hydrocortisone versus placebo reduce mortality at 28 days?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
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In adult patients with severe septic shock, does hydrocortisone versus placebo reduce mortality at 28 days?
Continue reading »In patients with suspected acute coronary syndrome does a rapid diagnostic pathway allow early discharge from hospital without more adverse effects when compared with a conventional diagnostic assessment and discharge plan?
Continue reading »Does High Frequency Oscillatory Ventilation (HFOV) improve mortality in patients with new onset moderate-severe ARDS compared with standard ventilation?
Continue reading »In patients with corneal abrasions, is topical tetracaine, compared with saline, for 24 hours a safe and effective analgesic?
Continue reading »Does High Frequency Oscillatory Ventilation (HFOV), compared with conventional ventilation, improve 30 day mortality in patients with ARDS?
Continue reading »In patients with cardiac arrest does adrenaline, compared to placebo, improve survival to hospital discharge?
Continue reading »In high-risk patients undergoing gastrointestinal surgery, does a cardiac output-guided haemodynamic therapy algorithm compared to clinician-guided standard therapy reduce death and major morbidity within 30 days?
Continue reading »In patients who present with an upper gastrointestinal (GI) bleed, does a restrictive transfusion goal compared with a liberal transfusion goal affect mortality?
Continue reading »In patients with an out-of-hospital cardiac arrest does removing the use of intravenous medications improve survival?
Continue reading »In patients with out-of-hospital (OOH) cardiac arrest is the use of adrenaline, compared to not using adrenaline, associated with an improved mortality?
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