Tag: Steroids

REMAP CAP: Corticosteroids

1 September 2025 Generic Contributor Intensive Care Medicine Leave a comment

Effect of hydrocortisone on mortality in patients with severe community-acquired pneumonia: The REMAP-CAP Corticosteroid Domain Randomized Clinical Trial Angus. ICM 2025; doi: https://doi.org/10.1007/s00134-025-07861-w Clinical Question In adult patients with severe community acquired pneumonia (CAP) requiring ICU admission, does a 7-day course of intravenous hydrocortisone reduce 90-day mortality? Background Community-acquired pneumonia (CAP) remains a leading cause of ICU admissions and mortality […]

CAPE COD

22 March 2023 George Walker Intensive Care Medicine, Summaries Leave a comment

In patients with severe community acquired pneumonia (CAP) does the use of hydrocortisone compared to a placebo reduce 28-day mortality?

COVID STEROID 2

9 September 2021 David Slessor Intensive Care Medicine, Summaries Leave a comment

In patients with severe COVID, does 12mg dexamethasone vs 6mg dexamethasone increase the number of days alive without life support at 28 days?

REMAP-CAP

11 September 2020 George Walker Intensive Care Medicine, Summaries Leave a comment

In patients with severe COVID-19, does intravenous hydrocortisone (either as a fixed dose or restricted to when shock is clinically evident) compared with standard care, improve 21-day organ support free days?

RECOVERY: COVID-19 dexamethasone

3 July 2020 Celia Bradford Intensive Care Medicine Leave a comment

In hospitalised patients with SARS-CoV-2 infection does dexamethasone in additional to usual care, compared to usual care alone, reduce 28-day mortality?

APROCCHSS

16 March 2018 Adrian Wong Intensive Care Medicine Leave a comment

In critically ill patients with septic shock, does the combination of hydrocortisone plus fludrocortisone therapy reduce 90 day mortality?

ADRENAL

20 January 2018 David Slessor Intensive Care Medicine 4 comments

In critically ill patients with septic shock, does hydrocortisone compared with placebo, reduce 90 day mortality?

Steroids in Sepsis

5 January 2018 Steve Mathieu Blog, Editorial 4 comments

In patients with septic shock, do corticosteroids compared to placebo reduce mortality?
This is an editorial blog post in anticipation of the ADRENAL trial results to be presented at #CCR18.

COIITSS

5 January 2018 Duncan Chambler Intensive Care Medicine Leave a comment

In patients with septic shock who are treated with corticosteroids, does tight glycaemic control (4.44–6.1 mmol/l) compared with less-tight glycaemic control (<8.3 mmol/l) reduce in-hospital mortality?

Marik

3 February 2017 Steve Mathieu Intensive Care Medicine 12 comments

Does intravenous vitamin C, hydrocortisone and thiamine in addition to standard treatment, improve mortality in ICU patients with severe sepsis or septic shock, compared with standard treatment alone?

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