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In critically ill patients requiring blood, does transfusion with “fresh” RBC’s (stored for 8 days or less) compared with standard issue RBCs (stored 2-42 days) reduce 90 day mortality?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
In critically ill patients requiring blood, does transfusion with “fresh” RBC’s (stored for 8 days or less) compared with standard issue RBCs (stored 2-42 days) reduce 90 day mortality?
Continue reading »In adults undergoing cardiac surgery, does a restrictive transfusion strategy (Hb > 75 g/l) compared to a liberal transfusion strategy (Hb > 90 g/l) lead to fewer infections and ischaemic events within 3 months?
Continue reading »In trauma patients with or at risk of significant haemorrhage, does the early administration of a short course of tranexamic acid (TXA) affect the mortality, incidence of occlusive events and the amount of blood transfused?
Continue reading »In patients with severe trauma and predicted to require massive transfusion, does the use of a transfusion protocol using a 1:1:1 ratio of plasma to platelets to red blood cells (RBCs) compared to 1:1:2 improve mortality?
Continue reading »In patients with septic shock, does blood transfusion at a lower or higher haemoglobin threshold improve mortality?
Continue reading »In patients who present with an upper gastrointestinal (GI) bleed, does a restrictive transfusion goal compared with a liberal transfusion goal affect mortality?
Continue reading »In patients admitted to ICU does a restrictive vs. liberal blood transfusion strategy alter mortality?
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