FEAST
In paediatric patients with severe febrile illnesses, in a resource limited setting, do fluid boluses with albumin vs. saline vs. no fluid boluses affect mortality?
Continue reading »Year: 2010-2013
These are summaries of trials published in the early part of this decade.
EUSOS
What is the clinical outcome of patients after major non-cardiac surgery in Europe?
Continue reading »Bouwes
In patients treated with therapeutic hypothermia following cardiac arrest, can clinical examination, neuronspecific enolase (NSE), and median nerve somatosensory-evoked potentials (SEPs) predict poor outcome?
Continue reading »Determann
In mechanically ventilated patients without acute lung injury or acute respiratory distress (ALI/ARDS), does lower tidal volume ventilation at 6 ml/kg (Vt-low), compared to conventional tidal volume ventilation at 10 ml/kg (Vt-high), reduce cytokine levels associated with lung injury?
Continue reading »CRASH-2
In trauma patients with or at risk of significant haemorrhage, does the early administration of a short course of tranexamic acid (TXA) affect the mortality, incidence of occlusive events and the amount of blood transfused?
Continue reading »ACURASYS
In patients with moderate-severe ARDS does the early use of a neuromuscular blocking agent improve mortality?
Continue reading »CHEST
In critically ill patients requiring fluid resuscitation, does 6% hydroxyethyl starch (6% HES) compared to 0.9% sodium chloride (Saline) reduce mortality at 90 days?
Continue reading »Morelli
Does the use of the short-acting β-blocker esmolol effectively control heart rate (HR) in patients with septic shock?
Continue reading »PROWESS-SHOCK
In patients with septic shock, does Activated Protein C (also known as drotrecogin alfa or DrotAA) compared with placebo reduce mortality?
Continue reading »Yeatts
In adults requiring emergency intubation, does video laryngoscopy (VL) compared to direct laryngoscopy (DL) lead to better or worse in-hospital mortality?
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