Year: 2010-2013

These are summaries of trials published in the early part of this decade.

Doig

12 September 2014 David Slessor Intensive Care Medicine Leave a comment

In critically ill patients with relative contraindications to early enteral nutrition (EN), does providing early parenteral nutrition (PN), improve mortality?

HOPE-ICU

29 August 2014 David Slessor Intensive Care Medicine One comment

In critically ill patients does early treatment with haloperidol decrease the time that survivors spend in delirium or coma?

REDUCE

Is short-term (5 days) systemic glucocorticoid treatment in patients with COPD exacerbation as good as conventional (14 days) treatment in clinical outcome and does it decrease the overall exposure to steroids?

VSE

11 August 2014 David Slessor Emergency Medicine, Intensive Care Medicine 2 comments

In patients in cardiac arrest, does vasopressin + epinephrine during CPR combined with steroid supplementation during and after CPR, improve survival to discharge with a good neurological outcome, in comparison to the use of epinephrine alone?

TracMan

8 August 2014 Duncan Chambler Intensive Care Medicine Leave a comment

In mechanically ventilated adult patients with a high risk of prolonged ventilation, does early tracheostomy compared with late tracheostomy reduce mortality at 30 days?

Strom

18 July 2014 Duncan Chambler Intensive Care Medicine Leave a comment

In adult patients undergoing mechanical ventilation, does a strategy involving no continuous sedation, compared to a strategy of continuous sedation by infusion with a daily interruption, reduce the number of days of mechanical ventilation in the first 4 weeks?

MOPETT

26 June 2014 David Slessor Emergency Medicine, Intensive Care Medicine Leave a comment

In patients with moderate Pulmonary Embolism (PE), does low dose thrombolysis + anticoagulation, compared with anticoagulation alone, reduce pulmonary artery pressure at 28 months?

OSCILLATE

28 May 2014 David Slessor Intensive Care Medicine One comment

Does High Frequency Oscillatory Ventilation (HFOV) improve mortality in patients with new onset moderate-severe ARDS compared with standard ventilation?

Jacobs

22 May 2014 David Slessor Emergency Medicine, Intensive Care Medicine Leave a comment

In patients with cardiac arrest does adrenaline, compared to placebo, improve survival to hospital discharge?

Villanueva

20 May 2014 David Slessor Emergency Medicine, Intensive Care Medicine Leave a comment

In patients who present with an upper gastrointestinal (GI) bleed, does a restrictive transfusion goal compared with a liberal transfusion goal affect mortality?

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