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In critically ill patients with acute altered level of consciousness and no recent seizures, does continuous EEG (cEEG) compared to repeated routine EEG (rEEG) correlate with reduced mortality?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
A collection of TBL summaries relevant to Intensive Care Medicine
In critically ill patients with acute altered level of consciousness and no recent seizures, does continuous EEG (cEEG) compared to repeated routine EEG (rEEG) correlate with reduced mortality?
Continue reading »In adults presenting to the ED with a corneal abrasion is topical tetracaine more effective than placebo to control pain at a 24-48 hour follow up appointment?
Continue reading »In patients with or at risk of Acute Respiratory Distress Syndrome (ARDS), can nebulised heparin compared to placebo, accelerate recovery of physical function?
Continue reading »In patients with acute myocardial infarction and anaemia is a restrictive, compared with a liberal transfusion strategy, non-inferior with respect to major adverse cardiovascular outcomes at 30 days?
Continue reading »In patients with acute hypoxaemic respiratory failure, does a lower vs higher oxygenation target reduce mortality at 90 days?
Continue reading »In hospitalised adult patients with severe or critical COVID-19 pneumonia, does tocilizumab plus standard care compared with standard care alone, improve clinical outcomes at day 15?
Continue reading »In patients with chronic subdural haemorrhage, what effect does dexamethasone compared with placebo have on neurological outcome at 6 months?
Continue reading »In critically ill patients with COVID-19, do the IL-6 receptor antagonists, tocilizumab and sarilumab, compared with standard care, improve respiratory and cardiovascular organ support free days up to day 21?
Continue reading »In hospitalised patients with severe acute respiratory syndrome due to coronavirus 2 (SAR-CoV-2), does tocilizumab compared with placebo, reduce intubation rates or mortality?
Continue reading »In adults suffering out of hospital cardiac arrest (OHCA) presenting with an initial rhythm of VF or pulseless VT, does the implementation of early ECMO facilitated resuscitation compared to standard ACLS resuscitation improve survival to hospital discharge?
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