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Does intravenous vitamin C, hydrocortisone and thiamine in addition to standard treatment, improve mortality in ICU patients with severe sepsis or septic shock, compared with standard treatment alone?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
A category to collect all the summaries, so that they can be used in menus and widgets. Please don’t expand this – “Specialties” and “Special Topics” have been created as a custom category sets for the clinical topics.
Does intravenous vitamin C, hydrocortisone and thiamine in addition to standard treatment, improve mortality in ICU patients with severe sepsis or septic shock, compared with standard treatment alone?
Continue reading »In patients with drained cutaneous abscesses does trimethoprim-sulfamethoxazole compared with placebo increase clinical cure rates?
Continue reading »In hospitalised patients with community-acquired pneumonia (CAP), is five days of antibiotic therapy non-inferior to standard practice with respect to clinical improvement?
Continue reading »In patients with convulsive status epilepticus, does the addition of therapeutic hypothermia to standard care improve neurological outcomes?
Continue reading »In elderly patients following non-cardiac surgery, does a low dose dexmedetomidine infusion, compared with placebo, decrease the incidence of delirium?
Continue reading »In critically ill adults requiring renal replacement therapy, does higher intensity dialysis compared to lower intensity dialysis reduce mortality?
Continue reading »In critically ill patients who are anaemic, does early administration of intravenous iron compared to placebo reduce the requirement for blood transfusion?
Continue reading »In patients presenting to the Emergency Department with chest pain, does the HEART Pathway compared with usual care, reduce objective cardiac testing?
Continue reading »In adult Emergency Department patients requiring intravenous sedation for noxious procedures, does a combination of propofol and ketamine (ketofol), compared with single-agent propofol, cause fewer adverse respiratory events?
Continue reading »In medically-qualified anaesthetist, does the use of the transverse ultrasound technique compared to the longitudinal orientation result in faster identification of the cricothyroid membrane?
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