TRANSFUSE
In critically ill patients requiring transfusion, does the transfusion of the freshest available red cells compared to standard care impact on patient mortality?
Continue reading »Category: Summaries
A category to collect all the summaries, so that they can be used in menus and widgets. Please don’t expand this – “Specialties” and “Special Topics” have been created as a custom category sets for the clinical topics.
ATACAS TXA
In adult patients undergoing elective coronary-artery surgery does tranexamic acid (TXA) compared to a placebo increase the risk of death or thrombotic complications within the first 30 days after surgery?
Continue reading »ATACAS Asp
In adults undergoing elective coronary artery graft surgery does the administration of aspirin prior to surgery compared to a placebo result in increased mortality or thrombotic complications?
Continue reading »DETO2X-AMI
In patients with suspected myocardial infarction with no baseline hypoxia, does oxygen therapy or room air improve all-cause mortality at 1 year?
Continue reading »60/60 sign for Acute PE
In patients with suspected acute pulmonary embolism, do echo features of disturbed right ventricular ejection allow accurate diagnosis?
Continue reading »Seymour
In patients with severe sepsis or septic shock, does a faster time to completion of a 3 hour bundle of care, compared with a slower time, affect in hospital mortality?
Continue reading »POISE 1
In patients undergoing non-cardiac surgery, do beta-blockers compared to placebo reduce the composite of death, MI or non-fatal cardiac arrest?
Continue reading »SHENFU
In patients with in-hospital cardiac arrest, does Shenfu (a traditional Chinese
medicine), improve 28 day mortality?
EPICC
Intensive versus standard physical rehabilitation therapy in the critically ill (EPICC): a multicentre, parallel-group, randomised controlled trial Wright. 2017. Thorax 2017: 0:1–9. doi:10.1136/thoraxjnl-2016-209858 Clinical Question Does an increased intensity of ICU based physical rehabilitation therapy improve improve long-term physical quality of life compared with a standard intensity of physical rehabilitation? Background Physical and psychological recovery after a period of critical […]
Continue reading »TTM 48
In adults with out of hospital cardiac arrest (OOHCA) due to a presumed cardiac cause, who are post ‘return of spontaneous circulation’ (ROSC), does cooling to 33°C for 48 hours, compared with 24 hours, improve improved neurological outcomes at 6 months?
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