MOnIToR trial
In brain-dead organ donors does the use of protocolised fluid therapy compared to usual care improve the number of organs transplanted?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
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In brain-dead organ donors does the use of protocolised fluid therapy compared to usual care improve the number of organs transplanted?
Continue reading »In trauma patients with or at risk of significant haemorrhage, does the early administration of a short course of tranexamic acid (TXA) affect the mortality, incidence of occlusive events and the amount of blood transfused?
Continue reading »In patients with suspected acute coronary syndrome (ACS) does a novel accelerated diagnostic protocol (ADP) identify low risk patients suitable for discharge after a single high-sensitivity troponin T (hs-cTnT)?
Continue reading »In patients with severe trauma and predicted to require massive transfusion, does the use of a transfusion protocol using a 1:1:1 ratio of plasma to platelets to red blood cells (RBCs) compared to 1:1:2 improve mortality?
Continue reading »Does a nurse-implemented, goal-directed sedation protocol result in fewer ventilator days in children with acute respiratory failure?
Continue reading »In critically ill patients with low serum vitamin D levels, does high-dose vitamin D supplementation compared with placebo reduce hospital length of stay?
Continue reading »In patients with moderate-severe ARDS does the early use of a neuromuscular blocking agent improve mortality?
Continue reading »In critically ill patients requiring fluid resuscitation, does 6% hydroxyethyl starch (6% HES) compared to 0.9% sodium chloride (Saline) reduce mortality at 90 days?
Continue reading »In patients who are in refractory cardiac arrest, does protocolised management involving mechanical CPR, Hypothermia, ECMO and early reperfusion improve survival rate?
Continue reading »In patients with refractory ventricular fibrillation does the use of esmolol improve mortality?
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