REALITY
In patients with acute myocardial infarction and anaemia is a restrictive, compared with a liberal transfusion strategy, non-inferior with respect to major adverse cardiovascular outcomes at 30 days?
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HOT-ICU
In patients with acute hypoxaemic respiratory failure, does a lower vs higher oxygenation target reduce mortality at 90 days?
Continue reading »TOCIBRAS
In hospitalised adult patients with severe or critical COVID-19 pneumonia, does tocilizumab plus standard care compared with standard care alone, improve clinical outcomes at day 15?
Continue reading »Dex-CSDH
In patients with chronic subdural haemorrhage, what effect does dexamethasone compared with placebo have on neurological outcome at 6 months?
Continue reading »PlasmAr
es convalescent plasma compared with placebo, improve patients’ clinical status at 30 days?
Continue reading »REMAP-CAP IL-6
In critically ill patients with COVID-19, do the IL-6 receptor antagonists, tocilizumab and sarilumab, compared with standard care, improve respiratory and cardiovascular organ support free days up to day 21?
Continue reading »BACC
In hospitalised patients with severe acute respiratory syndrome due to coronavirus 2 (SAR-CoV-2), does tocilizumab compared with placebo, reduce intubation rates or mortality?
Continue reading »DANMASK-19
In adults in Denmark reported to spend three hours or more outside of the home during the early stages of the COVID-19 pandemic, did a recommendation to wear a surgical face mask, compared with no recommendation to wear a surgical face mask, reduce SARS-CoV-2 infection at one month?
Continue reading »ARREST
In adults suffering out of hospital cardiac arrest (OHCA) presenting with an initial rhythm of VF or pulseless VT, does the implementation of early ECMO facilitated resuscitation compared to standard ACLS resuscitation improve survival to hospital discharge?
Continue reading »RECOVERY: COVID-19 Kaletra
In patients admitted to hospital with COVID-19, does Lopinavir-ritonavir therapy (Kaletra) compared to usual care, reduce 28-day mortality?
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