ATACH-2 Trial
In patients with acute intracerebral haemorrhage and who are hypertensive, does rapid lowering of systolic blood pressure compared to standard therapy improve patient outcomes ?
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REACT 2
In patients with severe trauma does immediate total body CT scanning compared with standard workup with selective CT scanning, reduce hospital mortality?
Continue reading »Erythro-Emerge
In patients undergoing anaesthesia for an emergency procedure, does erythromycin compared to placebo reduce gastric content volume?
Continue reading »ELAIN
In adult patients on ICU, does early initiation of RRT compared to delayed initiation of RRT reduce mortality at 90 days?
Continue reading »AKIKI
In critically ill patients with acute kidney injury does early compared with delayed initiation of renal replacement therapy (RRT) improve mortality at 60 days?
Continue reading »Kleine-Brueggeney
In patients having elective surgery and with a simulated difficult airway (using a cervical collar), does the choice of videolaryngoscope affect the first attempt intubation success rate?
Continue reading »Anderson
In patients with acute ischaemic stroke, is low-dose thrombolysis therapy with intravenous alteplase non-inferior to standard-dose therapy with respect to death and disability at 90 days?
Continue reading »Meacock
In patients presenting to an acute hospital, is presentation on a weekend day compared to presentation on a week day associated with increased mortality?
Continue reading »Drakulovic
In patients who are mechanically ventilated does the semi-recumbent position vs. supine position reduce clinically suspected pneumonia?
Continue reading »Monnet
In patients who are mechanically ventilated, does the tidal volumes or compliance, affect the performance of pulse pressure variation to predict volume responsiveness? In addition, in patients with ARDS can a passive leg raise test or end-expiratory occlusion test predict fluid responsiveness?
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