Year: 2016

These are summaries of trials published in 2016.

RESCUEicp

In patients with a traumatic brain injury (TBI) and refractory intracranial hypertension, does decompressive craniectomy, result in more favourable mortality and neurological outcomes at 6 months, compared with barbiturate coma and continued medical management?

Philpot

2 September 2016 Celia Bradford Intensive Care Medicine Leave a comment

Do observers of simulated family conversations discussing organ donation respond more favourably to the discussion if it contains extra information about the benefits of donation compared to a standard conversation?

Morris

26 August 2016 Segun Olusanya Intensive Care Medicine Leave a comment

In patients with acute respiratory failure, does early delivery of a standardised ICU and hospital rehabilitation programme improve physical function and reduce hospital length of stay?

VANISH Trial

5 August 2016 Steve Mathieu Intensive Care Medicine 4 comments

Does early vasopressin use reduce the risk of kidney failure in patients with septic shock compared with norepinephrine?

PROCAMIO

29 July 2016 David Slessor Emergency Medicine 4 comments

In patients with wide QRS (probably ventricular) tachycardia, does intravenous procainamide compared with intravenous amiodarone reduce major adverse cardiac events?

HOT-ER

22 July 2016 Duncan Chambler Emergency Medicine, Intensive Care Medicine 2 comments

In hypoxic adults presenting to the emergency department, does nasal high-flow oxygen compared to standard oxygen therapy reduce the need for advanced respiratory support?

ATACH-2 Trial

15 July 2016 Adrian Wong Emergency Medicine, Intensive Care Medicine 3 comments

In patients with acute intracerebral haemorrhage and who are hypertensive, does rapid lowering of systolic blood pressure compared to standard therapy improve patient outcomes ?

REACT 2

8 July 2016 David Slessor Emergency Medicine 11 comments

In patients with severe trauma does immediate total body CT scanning compared with standard workup with selective CT scanning, reduce hospital mortality?

The Swedish Spinal Stenosis Study

1 July 2016 Celia Bradford Peri-operative Medicine, Summaries One comment

In patients with lumbar spinal stenosis at 1 or 2 adjacent vertebral levels, with or without spondylolisthesis, what is the efficacy of decompression surgery compared with decompression and fusion surgery, on functional outcome assessed 2 years post-operatively?

ELAIN

17 June 2016 Segun Olusanya Intensive Care Medicine 4 comments

In adult patients on ICU, does early initiation of RRT compared to delayed initiation of RRT reduce mortality at 90 days?

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