Critical Care Evidence Updates – June 21
What’s new in the Critical Care literature – monthly updates
Continue reading »Year: 2021
COBI
In adult patients with moderate to severe traumatic brain injury, does a continuous infusion of 20% saline, compared with standard care along, improve neurological outcomes at six months?
Continue reading »TTM2
In patients who are unconscious following out-of-hospital cardiac arrest, does targeted hypothermia compared with targeted normothermia, impact all-cause mortality?
Continue reading »TRAAP2
In patients undergoing caesarean section (CS) does the administration of tranexamic acid (TXA) when compared to placebo result in a lower incidence of calculated estimated blood loss of red blood cell transfusion by day 2?
Continue reading »MENDS2
In mechanically ventilated adults with sepsis, does the use of dexmedetomidine, compared with propofol, for continuous sedation improve the number of days alive without delirium or coma?
Continue reading »Sjöblom
In adult patients undergoing rapid sequence intubation for emergency surgery, does pre-oxygenation with high-flow nasal oxygen, compared with standard face-mask oxygen, reduce the incidence of oxygen desaturation?
Continue reading »ULTRA
In adults presenting with subarachnoid haemorrhage (SAH), does ultra early short term treatment with tranexamic acid improve clinical outcome at 6 months?
Continue reading »SHIPMAN
In adults presenting to the ED with a corneal abrasion is topical tetracaine more effective than placebo to control pain at a 24-48 hour follow up appointment?
Continue reading »CHARLI
In patients with or at risk of Acute Respiratory Distress Syndrome (ARDS), can nebulised heparin compared to placebo, accelerate recovery of physical function?
Continue reading »REALITY
In patients with acute myocardial infarction and anaemia is a restrictive, compared with a liberal transfusion strategy, non-inferior with respect to major adverse cardiovascular outcomes at 30 days?
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