RECOVERY: COVID-19 dexamethasone
In hospitalised patients with SARS-CoV-2 infection does dexamethasone in additional to usual care, compared to usual care alone, reduce 28-day mortality?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
In hospitalised patients with SARS-CoV-2 infection does dexamethasone in additional to usual care, compared to usual care alone, reduce 28-day mortality?
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In critically ill patients with Vitamin D deficiency and a high risk of death, does early enteral replacement of Vitamin D3 compared with placebo improve survival at 90 days?
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In patients with severe sepsis what is the sensitivity of blood cultures taken after the initiation of antimicrobial therapy?
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In patients older than 65-years with vasodilatory hypotension receiving vasopressors, does a target mean arterial pressure (MAP) of 60-65mmHg compared with usual care impact mortality?
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Does treatment with vitamin C, hydrocortisone, and thiamine lead to a more rapid resolution of septic shock compared with hydrocortisone alone?
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In patients undergoing major surgery who are at high risk of complications, does light anaesthesia (BIS 50) compared with deep anaesthesia (BIS 35) improve survival at 1-year?
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In mechanically ventilated ICU patients does a conservative use of oxygen therapy compared to usual oxygen therapy affect the number of ventilator-free-days?
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In obese patients, does the use of recruitment maneuvers with high PEEP, compared with low PEEP, decrease postoperative pulmonary complications?
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In patients with cirrhosis and acute variceal bleeding, does early transjugular intrahepatic portosystemic shunt (TIPS) compared to standard care increase transplant-free survival?
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In critically ill adults, does haloperidol 1 mg or haloperidol 2 mg given three times a day compared to placebo reduce mortality?
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