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In mechanically ventilated, critically ill patients receiving enteral nutrition does energy-dense feed (1.5kCal/ml) compared with routine feed (1kCal/ml) impact on 90 day all cause mortality?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
In mechanically ventilated, critically ill patients receiving enteral nutrition does energy-dense feed (1.5kCal/ml) compared with routine feed (1kCal/ml) impact on 90 day all cause mortality?
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In mechanically ventilated patients without acute respiratory distress syndrome (ARDS), does a low tidal volume ventilation strategy (6mL/Kg), compared to intermediate tidal volume strategy (10mL/Kg), reduce the number of ventilator-free and alive days at day 28?
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patients with septic shock and severe acute kidney injury, does early vs. delayed renal replacement therapy improve 90 day mortality?
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In adult patients with septic shock and high circulating endotoxin activity, does the use of polymyxin B haemoperfusion therapy significantly decrease 28-day mortality?
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This editorial blog has been written to complement the short presentation delivered by Duncan Chambler at the British Association of Indian Anaesthetists (BAOIA) 2018 conference in Newcastle.
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In critically ill patients with septic shock, does the use of terlipressin compared to norepinephrine reduced 28-day mortality?
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In critically ill adults with severe sepsis, does 6% hydroxyethyl starch (HES) compared to Ringer’s acetate reduce the incidence of death or end stage kidney failure?
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In selected non-trauma patients presenting to the emergency department with undifferentiated hypotension, does a standardised point-of-care ultrasound protocol, compared with usual care, improve 30 day or hospital survival?
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In critically ill patients with severe metabolic acidaemia (pH ≤7⋅20), does the infusion of sodium bicarbonate, compared with no infusion, to reach and maintain a targeted pH of 7⋅30 decrease the primary composite outcome of mortality by day 28 or the presence of at least one organ failure at day 7?
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In patients with sepsis, critical illness, stroke, trauma, myocardial infarction, cardiac arrest and those who had emergency surgery does a liberal oxygen strategy compared with a conservative oxygen strategy increase hospital mortality?
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