Search Results for “Sepsis” – Page 13

SCARLET

In adult patients with sepsis-associated coagulopathy does the administration of human recombinant thrombomodulin (rhsTM) compared to placebo reduce 28 day mortality?

EPVent2

Does titrating positive end-expiratory pressure (PEEP) with the use of an esophageal balloon to estimate pleural pressure improve outcomes compared with an empirical high PEEP –FiO2 strategy in patients with moderate – severe acute respiratory distress syndrome (ARDS)

SPICE III

24 May 2019 Celia Bradford Intensive Care Medicine 3 comments

In ventilated, critically ill patients, does the use of dexmedetomidine as the primary sedative agent compared with usual sedative agents effect 90 day mortality?

PreVent

17 May 2019 Daniel Lane Emergency Medicine, Intensive Care Medicine, Peri-operative Medicine One comment

In adult ICU patients undergoing tracheal intubation, does bag mask ventilation (BMV) between induction and laryngoscopy reduce the risk of hypoxaemia?

Woolum

26 April 2019 Jose Chacko Emergency Medicine, Intensive Care Medicine 3 comments

In patients with septic shock, does the administration of thiamine lead to more rapid lactate clearance and improved clinical outcomes?

MASTERS

29 March 2019 Alex Smith Peri-operative Medicine Leave a comment

In high-risk patients undergoing major abdominal surgery, does epidural analgesia compared with no epidural analgesia reduce mortality and morbidity?

ANDROMEDA-SHOCK

15 March 2019 Aidan Burrell Emergency Medicine, Intensive Care Medicine 7 comments

In adult patients with early septic shock, does peripheral perfusion-targeted resuscitation, compared to lactate level-targeted resuscitation, improve all cause mortality at 28 days?

iPROVE

22 February 2019 Doug Tunney Peri-operative Medicine Leave a comment

In adult patients undergoing abdominal surgery, with intermediate-to-high-risk of post-operative pulmonary complications, will an individualised perioperative open-lung ventilation strategy (iPROVE), compared with standard protective ventilation, result in fewer post-operative complications during the first 7 days post surgery