FiSh
In children with septic shock, does a restricted fluid bolus volume, compared with a standard fluid bolus volume, improve outcomes?
Continue reading »Category: Emergency Medicine
A collection of TBL summaries relevant to Emergency Medicine
AIRWAYS-2
In adult patients with non-traumatic out-of-hospital cardiac arrest, does a supraglottic airway device compared with tracheal intubation as the initial advanced airway management strategy, improve functional neurological outcome?
Continue reading »CULPRIT-SHOCK: One year follow up
In patients with acute myocardial infarction complicated by cardiogenic shock and evidence of multi-vessel disease on early diagnostic angiography, does immediate multi-vessel percutaneous coronary intervention (PCI) compared to culprit lesion only PCI (with staged revascularisation) improve outcome?
Continue reading »PAMPer
In severely injured patients at risk for haemorrhagic shock, does prehospital plasma resuscitation, compared with standard-care resuscitation (not including plasma administration), reduce 30-day mortality?
Continue reading »PARAMEDIC2
In adult patients with out-of-hospital cardiac arrest (OOHCA), does the administration of epinephrine compared to placebo improve survival?
Continue reading »Franklin
In infants (<12 months) with bronchiolitis and hypoxaemia (saturations <92%) in the emergency department or general paediatric ward, does early treatment with high flow therapy versus standard oxygen therapy result in fewer infants having treatment failure that leads to escalation of care?
Continue reading »6S
In critically ill adults with severe sepsis, does 6% hydroxyethyl starch (HES) compared to Ringer’s acetate reduce the incidence of death or end stage kidney failure?
Continue reading »SHoC-ED
In selected non-trauma patients presenting to the emergency department with undifferentiated hypotension, does a standardised point-of-care ultrasound protocol, compared with usual care, improve 30 day or hospital survival?
Continue reading »EXTEND IA TNK
In patients with anterior circulation strokes undergoing endovascular thrombectomy, is IV thrombolysis within 4.5 hours of stroke onset with tenecteplase, non-inferior to alteplase, at establishing reperfusion?
Continue reading »CASS
In septic and mechanically ventilated patients aged 50 or over, does 24 hours of induced hypothermia followed by 48 hours of normothermia improve 30-day mortality compared to routine care?
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