Zochios
In patients at high risk of respiratory complications after cardiac surgery, does the routine application of high-flow nasal oxygen compared to standard oxygen reduce hospital length of stay?
Continue reading »Category: Summaries
A category to collect all the summaries, so that they can be used in menus and widgets. Please don’t expand this – “Specialties” and “Special Topics” have been created as a custom category sets for the clinical topics.
TRACT Transfusion Volume
Transfusion Volume for Children with Severe Anaemia in Africa K.Maitland. New England Journal of Medicine August 1st 2019; 381:5; 420-431. doi: 10.1056/NEJMoa1900100 Clinical Question In African children presenting to hospital with severe anaemia, is a blood transfusion volume of 30 ml/kg superior to 20 ml/kg in reducing 28 day mortality? Background Severe anaemia is a major cause of death and […]
Continue reading »TRACT Tranfusion Timing
In children hospitalised with uncomplicated severe anaemia, is an immediate blood transfusion strategy superior to delayed transfusion in reducing 28-day mortality?
Continue reading »DRAIN
In adults with decompensated heart failure who are at high-risk of diuretic resistance, does furosemide administered by infusion compared to intermittent bolus increase the incidence of freedom from congestion at 72 hours?
Continue reading »PROBESE
In obese patients, does the use of recruitment maneuvers with high PEEP, compared with low PEEP, decrease postoperative pulmonary complications?
Continue reading »Simon
In adult critically ill patients with hypoxemic respiratory failure necessitating intubation, does high-flow nasal cannula (HFNC) compared to bag-valve-mask (BVM) for both pre-oxygenation and oxygenation during intubation reduce desaturation?
Continue reading »AVB-TIPS
In patients with cirrhosis and acute variceal bleeding, does early transjugular intrahepatic portosystemic shunt (TIPS) compared to standard care increase transplant-free survival?
Continue reading »IVC Filters
In severely injured trauma patients, where anticoagulation is contraindicated, does the use of prophylactic inferior vena cava filters reduce the incidence of pulmonary embolism (PE)?
Continue reading »OPTALYSE PE
In patients with intermediate risk PE, do low doses of tPA and short durations of ultrasound facilitated catheter directed thrombolysis, result in a reduction in RV:LV diameter at 48 hours?
Continue reading »ROSE
In patients with moderate to severe ARDS, does a strategy of early neuromuscular blockade with heavy sedation, as opposed to usual care with lighter sedation targets, result in a lower 90 day mortality?
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