Freemantle
Do patients admitted to English NHS hospitals on weekend days, compared to those admitted during week days, have an increased 30-day mortality?
Continue reading »Search Results for: Sepsis
STOP-IT
In patients with intraabdominal sepsis and who have received adequate source control, does a fixed short course of antibiotics result in similar treatment success compared to a longer duration of antibiotic therapy?
Continue reading »SHOCK 2
Intra-aortic balloon counterpulsation in acute myocardial infarction complicated by cardiogenic shock (IABP-SHOCK II): final 12 month results of a randomised, open-label trial IABP-SHOCK II Trial Investigators.NEJM;2012,367(14)1287-96, DOI: 10.1056/NEJMoa1208410 Clinical Question In patients with acute MI and cardiogenic shock, does intraaortic balloon counterpulsation (IABP) vs. medical therapy alone improve mortality? Design Randomised controlled trial Randomisation performed centrally via internet based program […]
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In adult patients with alcoholic hepatitis, does prednisolone and / or pentoxifylline compared to placebo reduce mortality?
Continue reading »Kumar
In patients with septic shock, what is the relationship between appropriateness of initial empiric antimicrobial therapy and survival?
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In adult patients with sepsis, severe sepsis or septic shock, is a single dose of etomidate for induction of anaesthesia, compared with any other induction, associated with a difference in mortality?
Continue reading »TITRe2
In adults undergoing cardiac surgery, does a restrictive transfusion strategy (Hb > 75 g/l) compared to a liberal transfusion strategy (Hb > 90 g/l) lead to fewer infections and ischaemic events within 3 months?
Continue reading »ProMISe
In adult patients with septic shock, does early goal-directed therapy (EGDT) compared with standard therapy reduce mortality at 90 days?
Continue reading »CHEST
In critically ill patients requiring fluid resuscitation, does 6% hydroxyethyl starch (6% HES) compared to 0.9% sodium chloride (Saline) reduce mortality at 90 days?
Continue reading »HARP2
In mechanically ventilated adults with acute respiratory distress syndrome (ARDS), does simvastatin compared to placebo reduce ventilator dependence?
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