Critical Care Evidence Updates – June 21
What’s new in the Critical Care literature – monthly updates
Continue reading »Category: Evidence-based Medicine
Bayesian Statistics
Bayesian Statistics “Under Bayes’ Theorem, no theory is perfect. Rather it is a work in progress, always subject to refinement and further testing” Nate Silver Introduction With the recent publication of the REMAP-CAP steroid arm and the Bayesian post-hoc re-analysis of the EOLIA trial, it appears Bayesian statistics are appearing more frequently in critical care trials. The purpose of this […]
Continue reading »P-Value
P-values – interpreting the evidence series
Continue reading »Critical Appraisal – Glossary
Rather than reinvent the wheel, we are delighted to include a link to the RCEM Critical Appraisal Dictionary. The RCEM learning site provides excellent open access educational resources, including critical care appraisal modules
Continue reading »Type 1 and 2 Errors
In statistical hypothesis testing, a type I error is the incorrect rejection of a true null hypothesis (a “false positive”), while a type II error is incorrectly retaining a false null hypothesis (a “false negative”). The more you try and avoid a Type I error (false positive), the more likely a Type II error (false negative) may happen. Researchers have found that an alpha level of 5% is a good balance between these two issues
Continue reading »Fragility Index
Fragility Index is the minimum number of patients whose status would have to change from a “non-event” (not having the primary endpoint) to an “event” (having the primary end point) in order to turn a statistically significant result to a nonsignificant result. It is a simple metric to calculate and use.
Reporting the Fragility Index in RCTs may help readers make more informed decisions about the confidence warranted by RCT results
Continue reading »Critical Care Symposium 2017
Slides and handout from the the ‘Critical Care Game Changers’ (updates in critical care) presentation at Critical Care Symposium 2017
Continue reading »Keeping Up To Date With The Medical Literature
Keeping up to date with the medical literature – Dave Slessor
Continue reading »Evidence-based Medicine Blog
Welcome to our blog. There will be lots of educational posts here to teach EBM skills such as biostatistics, critical appraisal and clinical interpretation of research.
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