A compendium of critical appraisals in Intensive Care Medicine research and related specialties
A category to collect all the summaries, so that they can be used in menus and widgets. Please don’t expand this – “Specialties” and “Special Topics” have been created as a custom category sets for the clinical topics.
In patients with severe trauma and predicted to require massive transfusion, does the use of a transfusion protocol using a 1:1:1 ratio of plasma to platelets to red blood cells (RBCs) compared to 1:1:2 improve mortality?
Continue reading »Does a nurse-implemented, goal-directed sedation protocol result in fewer ventilator days in children with acute respiratory failure?
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In critically ill patients with low serum vitamin D levels, does high-dose vitamin D supplementation compared with placebo reduce hospital length of stay?
Continue reading »In patients with moderate-severe ARDS does the early use of a neuromuscular blocking agent improve mortality?
Continue reading »In critically ill patients requiring fluid resuscitation, does 6% hydroxyethyl starch (6% HES) compared to 0.9% sodium chloride (Saline) reduce mortality at 90 days?
Continue reading »In patients who are in refractory cardiac arrest, does protocolised management involving mechanical CPR, Hypothermia, ECMO and early reperfusion improve survival rate?
Continue reading »In patients with refractory ventricular fibrillation does the use of esmolol improve mortality?
Continue reading »In mechanically ventilated adults with acute respiratory distress syndrome (ARDS), does simvastatin compared to placebo reduce ventilator dependence?
Continue reading »In critically ill patients, does parenteral nutrition compared with enteral nutrition improve mortality?
Continue reading »In mechanically ventilated and sedated patients, do Spontaneous Awakening Trials (SAT) in addition to Spontaneous Breathing Trials (SBT) reduce dependence on mechanical ventilation?
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