Category: Peri-operative Medicine

PAC-MAN

Pulmonary Artery Catheters in patient Management PAC-MAN study group, Lancet 2005;366;472-477 Clinical Question In critically ill patients, does the use of a pulmonary artery catheter (PAC) reduce mortality? Design Randomised controlled trial Non-blinded Stratified by age and presumptive clinical syndrome Intention to treat analysis Power calculation: 1281 patients would allow detection of a 10% change in absolute hospital mortality, with […]

OPTIMISE

21 May 2014 Duncan Chambler Peri-operative Medicine One comment

In high-risk patients undergoing gastrointestinal surgery, does a cardiac output-guided haemodynamic therapy algorithm compared to clinician-guided standard therapy reduce death and major morbidity within 30 days?