Fragility Index

Fragility Index is the minimum number of patients whose status would have to change from a “non-event” (not having the primary endpoint) to an “event” (having the primary end point) in order to turn a statistically significant result to a nonsignificant result. It is a simple metric to calculate and use.

Reporting the Fragility Index in RCTs may help readers make more informed decisions about the confidence warranted by RCT results

Continue reading »
1 6 7 8